Professor paul tofts has worked on the physical aspects of quantitative brain imaging since the early days of clinical nmr he was the first to measure in vivo concentrations of metabolites and to use dynamic imaging to measure blood brain barrier permeability and extra cellular space in multiple sclerosis. Quantitative mri of the brain measuring changes caused by disease 1st edition by paul tofts editor visit amazons paul tofts page find all the books read about the author and more see search results for this author are you an author learn about author central. Pdf on oct 1 2004 m maier and others published quantitative mri of the brain measuring changes caused by disease find read and cite all the research you need on researchgate . It is clear that it has been written by people who have hands on experience of mr and who have had to deal with the issues associated with quantification in all forms of mr use diffusion magnetisation transfer spectroscopy contrast enhanced mri functional mri blood perfusion and volume estimation and the various practicalities associated . This syllabus is for a presentation in the course quantitative mri approaches in clinical imaging organised by ismrm at stockholm may 2 nd 2010 this version december 13 th 2009 1 tofts ps quantitative mri of the brain measuring changes caused by disease john wiley 2003
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